To get from Perugia to Messina by train you can catch one of the 3 trains that everyday travel between these two cities. The first train to Messina leaves from Perugia at 06:40 and the last train departs at 17:56. If you choose a local train the trip lasts on average 11:14 hours. For your trip from Perugia to Messina by train you can choose to leave from one of Perugia main stations: Perugia Prices for next month range from € 22 to € 22. The most economic train is Intercity () that departs at 06:40 and arrives in Messina at 19:30 at € 22. On Wanderio you can compare all schedules, fares and railway companies to Messina and book the best itinerary starting from Perugia.