Perugia to Palermo trains might be a good value for money solution; travelling in Italy by train is often rather cheap and faster than taking a bus indeed. You can count on 4 daily rides to get from Perugia to Palermo. Trains leave from Perugia and arrive at Palermo Notarbartolo every about 3 hours on average. If travelling with Trenitalia, you need to know the Perugia to Palermo train schedule: the first train leaves at 17:56, while the last ride is at 22:21. A Perugia to Palermo train cost about 90.2 €. But how long is the train ride from Perugia to Palermo? Your journey takes about 20 hours on average.