Pesaro to Palermo trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Pesaro and arrive at Palermo Notarbartolo every about 2 hours on average. If travelling with Trenitalia, you need to know the Pesaro to Palermo train schedule: the first train leaves at 13:09, while the last ride is at 20:36. A Pesaro to Palermo train cost about 97.55 €. But how long is the train ride from Pesaro to Palermo? Your journey takes about 20 hours on average.