Pescara to Messina trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Pescara Centrale and arrive at Messina Centrale every about 4 hours on average. If travelling with Trenitalia, you need to know the Pescara to Messina train schedule: the first train leaves at 07:04, while the last ride is at 17:40. A Pescara to Messina train cost about 103.8 €. But how long is the train ride from Pescara to Messina? Your journey takes about 13 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Pescara to Messina and find low cost tickets starting from 78 €!