Pescara to Syracuse trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Pescara Porta Nuova and arrive at Siracusa every about 4 hours on average. If travelling with Trenitalia, you need to know the Pescara to Syracuse train schedule: the first train leaves at 07:08, while the last ride is at 17:21. A Pescara to Syracuse train cost about 100.8 €. But how long is the train ride from Pescara to Syracuse? Your journey takes about 16 hours on average.