Piacenza to Messina trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Piacenza and arrive at Messina Centrale every about 2 hours on average. If travelling with Trenitalia, you need to know the Piacenza to Messina train schedule: the first train leaves at 06:29, while the last ride is at 23:05. A Piacenza to Messina train cost about 64.5 €. But how long is the train ride from Piacenza to Messina? Your journey takes about 14 hours on average.