Pisa to Agrigento trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Pisa Centrale and arrive at Agrigento Bassa every about 4 hours on average. If travelling with Trenitalia, you need to know the Pisa to Agrigento train schedule: the first train leaves at 00:01, while the last ride is at 19:13. A Pisa to Agrigento train cost about 76.0 €. But how long is the train ride from Pisa to Agrigento? Your journey takes about 18 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Pisa to Agrigento and find low cost tickets starting from 33 €!