To get from Pisa a Casarano by train you can catch one of the 23 trains that everyday travel between Pisa Centrale and Lecce, the closest station to the city. For your trip from Pisa Centrale to Lecce by train you can choose to leave from one of Pisa Centrale main stations: Pisa Centrale, Salerno If travelling with Trenitalia, you need to know the Pisa Centrale to Lecce train schedule: the first train leaves at 05:39, while the last ride is at 20:32. A Pisa Centrale to Lecce train cost about 19.85 €. But how long is the train ride from Pisa Centrale to Lecce? Your journey takes about 9 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Pisa Centrale to Lecce and find low cost tickets starting from 48 €!