Pistoia to Messina trains might be a good value for money solution; travelling in Italy by train is often rather cheap and faster than taking a bus indeed. You can count on 5 daily rides to get from Pistoia to Messina. Trains leave from Pistoia and arrive at Messina Centrale every about 2 hours on average. If travelling with Trenitalia, you need to know the Pistoia to Messina train schedule: the first train leaves at 09:12, while the last ride is at 21:44. A Pistoia to Messina train cost about 92.3 €. But how long is the train ride from Pistoia to Messina? Your journey takes about 11 hours on average.