Pistoia to Palermo trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Pistoia and arrive at Palermo Notarbartolo every about 2 hours on average. If travelling with Trenitalia, you need to know the Pistoia to Palermo train schedule: the first train leaves at 16:12, while the last ride is at 21:44. A Pistoia to Palermo train cost about 98.1 €. But how long is the train ride from Pistoia to Palermo? Your journey takes about 18 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Pistoia to Palermo and find low cost tickets starting from 56 €!