Pistoia to Palermo trains might be a good value for money solution; travelling in Italy by train is often rather cheap and faster than taking a bus indeed. You can count on 7 daily rides to get from Pistoia to Palermo. Trains leave from Pistoia and arrive at Palermo Notarbartolo every about 2 hours on average. If travelling with Trenitalia, you need to know the Pistoia to Palermo train schedule: the first train leaves at 16:12, while the last ride is at 21:44. A Pistoia to Palermo train cost about 98.1 €. But how long is the train ride from Pistoia to Palermo? Your journey takes about 18 hours on average.