Pompei to Messina trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Pompei and arrive at Messina Centrale every about 4 hours on average. If travelling with Trenitalia, you need to know the Pompei to Messina train schedule: the first train leaves at 09:31, while the last ride is at 21:54. A Pompei to Messina train cost about 45.3 €. But how long is the train ride from Pompei to Messina? Your journey takes about 7 hours on average.