Pompei to Syracuse trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Pompei and arrive at Siracusa every about 4 hours on average. If travelling with Trenitalia, you need to know the Pompei to Syracuse train schedule: the first train leaves at 08:06, while the last ride is at 21:54. A Pompei to Syracuse train cost about 51.6 €. But how long is the train ride from Pompei to Syracuse? Your journey takes about 11 hours on average.