Pozzuoli to Messina trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Pozzuoli Solfatara and arrive at Messina Centrale every about 6 hours on average. If travelling with Trenitalia, you need to know the Pozzuoli to Messina train schedule: the first train leaves at 05:53, while the last ride is at 10:53. A Pozzuoli to Messina train cost about 58.0 €. But how long is the train ride from Pozzuoli to Messina? Your journey takes about 9 hours on average.