Pozzuoli to Palermo trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Pozzuoli Solfatara and arrive at Palermo Centrale every about 6 hours on average. If travelling with Trenitalia, you need to know the Pozzuoli to Palermo train schedule: the first train leaves at 05:53, while the last ride is at 10:53. A Pozzuoli to Palermo train cost about 71.5 €. But how long is the train ride from Pozzuoli to Palermo? Your journey takes about 13 hours on average.