Prato to Comiso trains might be a good value for money solution; travelling in Italy by train is often rather cheap and faster than taking a bus indeed. You can count on 2 daily rides to get from Prato to Comiso. Trains leave from Prato Porta al Serraglio and arrive at Comiso every about 6 hours on average. If travelling with Trenitalia, you need to know the Prato to Comiso train schedule: the first train leaves at 18:23, while the last ride is at 20:34. A Prato to Comiso train cost about 93.5 €. But how long is the train ride from Prato to Comiso? Your journey takes about 21 hours on average.