Ragusa to Manfredonia trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Ragusa and arrive at Reggio di Calabria Centrale every about 6 hours on average. If travelling with Trenitalia, you need to know the Ragusa to Manfredonia train schedule: the first train leaves at 07:50, while the last ride is at 07:50. A Ragusa to Manfredonia train cost about 31.95 €. But how long is the train ride from Ragusa to Manfredonia? Your journey takes about 8 hours on average.