Rome to Asti trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Roma Termini and arrive at Asti every about 1 hour on average. If travelling with Trenitalia, you need to know the Rome to Asti train schedule: the first train leaves at 06:15, while the last ride is at 17:00. A Rome to Asti train cost about 69.75 €. But how long is the train ride from Rome to Asti? Your journey takes about 6 hours on average. Trenitalia offers 1 direct trains between these two cities. Thanks to Trenitalia, offers, you can save on your trip from Rome to Asti and find low cost tickets starting from 29 €!