To get from Rome to Messina by train you can catch one of the 3 trains that everyday travel between these two cities. The first train to Messina leaves from Rome at 21:31 and the last train departs at 22:26. If you choose a local train the trip lasts on average 08:05 hours. For your trip from Rome to Messina by train you can choose to leave from one of Rome main stations: Roma Termini Tickets price depend on the departure time and train type, the most economic train ticket available this week is from € 62 to € 62. Prices for next month range from € 39 to € 39. The most economic train is InterCityNotte () that departs at 21:31 and arrives in Messina at 06:10 at € 39. On Wanderio you can compare all schedules, fares and railway companies to Messina and book the best itinerary starting from Rome.