Rome to Milan trains might be a good value for money solution; travelling in Italy by train is often rather cheap and faster than taking a bus indeed. You can count on 38 daily rides to get from Rome to Milan. Trains leave from Roma Termini and arrive at Milano Centrale every 20 minutes on average. The trip by train from Rome to Milan last on average 02:55 travelling with high-speed trains (Frecciarossa or Italotreno) If travelling with Trenitalia, you need to know the Rome to Milan train schedule: the first train leaves at 06:00, while the last ride is at 23:00. A Rome to Milan train cost about 34.60 €. But how long is the train ride from Rome to Milan? Your journey takes about 4 hours on average. Trenitalia offers 36 direct trains between these two cities. Thanks to Trenitalia offers, you can save on your trip from Rome to Milan and find prices starting from 19 €! Booking your train ticket a few weeks in advance though, you can find low cost trains from Rome to Milan with fares starting from 34.60€, saving 44% on average.