Rome to Milazzo trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Roma Termini and arrive at Milazzo every about 2 hours on average. If travelling with Trenitalia, you need to know the Rome to Milazzo train schedule: the first train leaves at 07:35, while the last ride is at 22:26. A Rome to Milazzo train cost about 44.90 €. But how long is the train ride from Rome to Milazzo? Your journey takes about 9 hours on average. Trenitalia offers 2 direct trains between these two cities. Thanks to Trenitalia, offers, you can save on your trip from Rome to Milazzo and find low cost tickets starting from 24 €! If you need to travel this week, prices range from 66.00 € to 181.00€. Booking your train ticket a few weeks in advance though, you can find low cost trains from Rome to Milazzo with fares starting from 29.90€, saving 71% on average.