Rome to Noto trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Roma Termini and arrive at Noto every about 6 hours on average. If travelling with Trenitalia, you need to know the Rome to Noto train schedule: the first train leaves at 07:35, while the last ride is at 07:35. A Rome to Noto train cost about 164.45 €. But how long is the train ride from Rome to Noto? Your journey takes about 12 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Rome to Noto and find low cost tickets starting from 63 €!