To get from Rome to Palermo by train you can catch one of the 9 trains that everyday travel between these two cities. The first train to Palermo leaves from Rome at 07:26 and the last train departs at 22:26. The trip by train from Rome to Palermo last on average 11:15 travelling with high-speed trains (Frecciarossa or Italotreno) If you choose a local train the trip lasts on average 11:08 hours. For your trip from Rome to Palermo by train you can choose to leave from one of Rome main stations: Roma Termini Tickets price depend on the departure time and train type, the most economic train ticket available this week is from € 80 to € 322. Prices for next month range from € 29 to € 73. The most economic train is Intercity () that departs at 07:26 and arrives in Palermo at 19:00 at € 29. On Wanderio you can compare all schedules, fares and railway companies to Palermo and book the best itinerary starting from Rome.