Rome to Syracuse trains might be a good value for money solution; travelling in Italy by train is often rather cheap and faster than taking a bus indeed. You can count on 7 daily rides to get from Rome to Syracuse. The trip by train from Rome to Syracuse last on average 10:54 travelling with high-speed trains (Frecciarossa or Italotreno) If travelling with Trenitalia, you need to know the Rome to Syracuse train schedule: the first train leaves at 07:35, while the last ride is at 22:26. A Rome to Syracuse train cost about 39.90 €. But how long is the train ride from Rome to Syracuse? Your journey takes about 11 hours on average. Trenitalia offers 2 direct trains between these two cities. Thanks to Trenitalia offers, you can save on your trip from Rome to Syracuse and find prices starting from 38 €! Booking your train ticket a few weeks in advance though, you can find low cost trains from Rome to Syracuse with fares starting from 29.90€, saving 61% on average.