Rome to Trapani trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Roma Termini and arrive at Trapani every about 2 hours on average. If travelling with Trenitalia, you need to know the Rome to Trapani train schedule: the first train leaves at 07:26, while the last ride is at 22:26. A Rome to Trapani train cost about 57 €. But how long is the train ride from Rome to Trapani? Your journey takes about 15 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Rome to Trapani and find low cost tickets starting from 51 €!