San Bonifacio to Mazara del Vallo trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from S. Bonifacio and arrive at Mazara del Vallo every about 4 hours on average. If travelling with Trenitalia, you need to know the San Bonifacio to Mazara del Vallo train schedule: the first train leaves at 17:14, while the last ride is at 18:14. A San Bonifacio to Mazara del Vallo train cost about 229.25 €. But how long is the train ride from San Bonifacio to Mazara del Vallo? Your journey takes about 21 hours on average.