San Giovanni Rotondo to Syracuse trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Siponto and arrive at Siracusa every about 6 hours on average. If travelling with Trenitalia, you need to know the San Giovanni Rotondo to Syracuse train schedule: the first train leaves at 06:41, while the last ride is at 17:43. A San Giovanni Rotondo to Syracuse train cost about 87.1 €. But how long is the train ride from San Giovanni Rotondo to Syracuse? Your journey takes about 15 hours on average.