San Nicola la Strada to Comiso trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Caserta and arrive at Comiso every about 12 hours on average. If travelling with Trenitalia, you need to know the San Nicola la Strada to Comiso train schedule: the first train leaves at 21:43, while the last ride is at 21:43. A San Nicola la Strada to Comiso train cost about 73.7 €. But how long is the train ride from San Nicola la Strada to Comiso? Your journey takes about 15 hours on average.