San Nicola la Strada to Syracuse trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Caserta and arrive at Siracusa every about 4 hours on average. If travelling with Trenitalia, you need to know the San Nicola la Strada to Syracuse train schedule: the first train leaves at 08:41, while the last ride is at 21:43. A San Nicola la Strada to Syracuse train cost about 57.7 €. But how long is the train ride from San Nicola la Strada to Syracuse? Your journey takes about 12 hours on average.