San Salvo to Messina trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Vasto-S. Salvo and arrive at Napoli Centrale, Messina Centrale every 60 minutes on average. If travelling with Trenitalia, you need to know the San Salvo to Messina train schedule: the first train leaves at 15:23, while the last ride is at 22:09. A San Salvo to Messina train cost about 14.65 €. But how long is the train ride from San Salvo to Messina? Your journey takes about 11 hours on average.