San Salvo to Syracuse trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Vasto-S. Salvo and arrive at Siracusa, Napoli Centrale every about 2 hours on average. If travelling with Trenitalia, you need to know the San Salvo to Syracuse train schedule: the first train leaves at 06:06, while the last ride is at 17:59. A San Salvo to Syracuse train cost about 14.65 €. But how long is the train ride from San Salvo to Syracuse? Your journey takes about 11 hours on average.