San Sebastiano to Messina trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Brescia, Salerno and arrive at Messina Centrale every about 1 hour on average. If travelling with Trenitalia, you need to know the San Sebastiano to Messina train schedule: the first train leaves at 17:25, while the last ride is at 22:35. A San Sebastiano to Messina train cost about 89.5 €. But how long is the train ride from San Sebastiano to Messina? Your journey takes about 13 hours on average. Thanks to Trenitalia, offers, you can save on your trip from San Sebastiano to Messina and find low cost tickets starting from 108 €! If you need to travel this week, prices range from 45.50 € to 45.50€. Booking your train ticket a few weeks in advance though, you can find low cost trains from San Sebastiano to Messina with fares starting from 19.90€, saving 56% on average.