To get from San Sebastiano to Syracuse by train you can catch one of the 7 trains that everyday travel between these two cities. The first train to Syracuse leaves from San Sebastiano at 07:05 and the last train departs at 22:35. If you choose a local train the trip lasts on average 15:40 hours. For your trip from San Sebastiano to Syracuse by train you can choose to leave from one of San Sebastiano main stations: Brescia Tickets price depend on the departure time and train type, the most economic train ticket available this week is from € 122 to € 144. The most economic train is Frecciargento () that departs at 07:05 and arrives in Syracuse at 22:45 at € 122. On Wanderio you can compare all schedules, fares and railway companies to Syracuse and book the best itinerary starting from San Sebastiano.