San Severo to Messina trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from S. Severo and arrive at Messina Centrale every about 6 hours on average. If travelling with Trenitalia, you need to know the San Severo to Messina train schedule: the first train leaves at 07:10, while the last ride is at 07:10. A San Severo to Messina train cost about 76.8 €. But how long is the train ride from San Severo to Messina? Your journey takes about 12 hours on average.