San Severo to Niscemi trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from S. Severo and arrive at Niscemi every about 2 hours on average. If travelling with Trenitalia, you need to know the San Severo to Niscemi train schedule: the first train leaves at 06:16, while the last ride is at 21:19. A San Severo to Niscemi train cost about 71.05 €. But how long is the train ride from San Severo to Niscemi? Your journey takes about 10 hours on average.