San Severo to Palermo trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from S. Severo and arrive at Palermo Notarbartolo every about 6 hours on average. If travelling with Trenitalia, you need to know the San Severo to Palermo train schedule: the first train leaves at 07:10, while the last ride is at 21:19. A San Severo to Palermo train cost about 70.9 €. But how long is the train ride from San Severo to Palermo? Your journey takes about 22 hours on average. Thanks to Trenitalia, offers, you can save on your trip from San Severo to Palermo and find low cost tickets starting from 54 €!