San Severo to Palermo trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from S. Severo and arrive at Palermo Notarbartolo every about 6 hours on average. If travelling with Trenitalia, you need to know the San Severo to Palermo train schedule: the first train leaves at 07:10, while the last ride is at 21:19. A San Severo to Palermo train cost about 70.9 €. But how long is the train ride from San Severo to Palermo? Your journey takes about 22 hours on average.