Sanremo to Messina trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from San Remo and arrive at Messina Centrale every about 4 hours on average. If travelling with Trenitalia, you need to know the Sanremo to Messina train schedule: the first train leaves at 11:50, while the last ride is at 20:15. A Sanremo to Messina train cost about 157.0 €. But how long is the train ride from Sanremo to Messina? Your journey takes about 19 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Sanremo to Messina and find low cost tickets starting from 58 €!