Sanremo to Syracuse trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from San Remo and arrive at Siracusa every about 3 hours on average. If travelling with Trenitalia, you need to know the Sanremo to Syracuse train schedule: the first train leaves at 11:50, while the last ride is at 20:15. A Sanremo to Syracuse train cost about 139.8 €. But how long is the train ride from Sanremo to Syracuse? Your journey takes about 22 hours on average.