To get from Sant'Anastasia a Casarano by train you can catch one of the 4 trains that everyday travel between Napoli Centrale and Lecce, the closest station to the city. For your trip from Napoli Centrale to Lecce by train you can choose to leave from one of Napoli Centrale main stations: Napoli Centrale If travelling with Trenitalia, you need to know the Napoli Centrale to Lecce train schedule: the first train leaves at 08:04, while the last ride is at 18:00. A Napoli Centrale to Lecce train cost about 32.1 €. But how long is the train ride from Napoli Centrale to Lecce? Your journey takes about 6 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Napoli Centrale to Lecce and find low cost tickets starting from 17 €!