Sant'Anastasia to Enna trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Reggio di Calabria Centrale, Casalnuovo di Napoli and arrive at Enna every about 2 hours on average. If travelling with Trenitalia, you need to know the Sant'Anastasia to Enna train schedule: the first train leaves at 11:16, while the last ride is at 21:21. A Sant'Anastasia to Enna train cost about 10.6 €. But how long is the train ride from Sant'Anastasia to Enna? Your journey takes about 8 hours on average.