Sant'Anastasia to Modica trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Casalnuovo di Napoli, Reggio di Calabria Centrale and arrive at Modica every about 4 hours on average. If travelling with Trenitalia, you need to know the Sant'Anastasia to Modica train schedule: the first train leaves at 08:56, while the last ride is at 13:19. A Sant'Anastasia to Modica train cost about 33.1 €. But how long is the train ride from Sant'Anastasia to Modica? Your journey takes about 10 hours on average.