Sant'Anastasia to Noto trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Reggio di Calabria Centrale, Casalnuovo di Napoli and arrive at Noto every about 2 hours on average. If travelling with Trenitalia, you need to know the Sant'Anastasia to Noto train schedule: the first train leaves at 07:09, while the last ride is at 13:19. A Sant'Anastasia to Noto train cost about 11.9 €. But how long is the train ride from Sant'Anastasia to Noto? Your journey takes about 8 hours on average.