Sant'Antimo to Acireale trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from S. Antimo-S. Arpino, Napoli Centrale and arrive at Acireale, Reggio di Calabria Centrale every about 2 hours on average. If travelling with Trenitalia, you need to know the Sant'Antimo to Acireale train schedule: the first train leaves at 08:37, while the last ride is at 23:53. A Sant'Antimo to Acireale train cost about 41.0 €. But how long is the train ride from Sant'Antimo to Acireale? Your journey takes about 9 hours on average.