Sant'Antimo to Milazzo trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from S. Antimo-S. Arpino, Napoli Centrale and arrive at Milazzo, Villa S. Giovanni, Reggio di Calabria Centrale every 60 minutes on average. If travelling with Trenitalia, you need to know the Sant'Antimo to Milazzo train schedule: the first train leaves at 08:23, while the last ride is at 23:53. A Sant'Antimo to Milazzo train cost about 44.90 €. But how long is the train ride from Sant'Antimo to Milazzo? Your journey takes about 7 hours on average. Trenitalia offers 2 direct trains between these two cities. Booking your train ticket a few weeks in advance though, you can find low cost trains from Sant'Antimo to Milazzo with fares starting from 9.90€, saving 78% on average.