Sant'Antimo to Varese trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from S. Antimo-S. Arpino and arrive at Roma Termini, Varese every 30 minutes on average. If travelling with Trenitalia, you need to know the Sant'Antimo to Varese train schedule: the first train leaves at 04:22, while the last ride is at 20:10. A Sant'Antimo to Varese train cost about 10.7 €. But how long is the train ride from Sant'Antimo to Varese? Your journey takes about 3 hours on average. Trenitalia offers 3 direct trains between these two cities.