Santeramo in Colle to Avola trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Santeramo and arrive at Avola every about 12 hours on average. If travelling with Trenitalia, you need to know the Santeramo in Colle to Avola train schedule: the first train leaves at 22:57, while the last ride is at 22:57. A Santeramo in Colle to Avola train cost about 59.65 €. But how long is the train ride from Santeramo in Colle to Avola? Your journey takes about 21 hours on average.