Santeramo in Colle to Milazzo trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Santeramo and arrive at Milazzo every about 12 hours on average. If travelling with Trenitalia, you need to know the Santeramo in Colle to Milazzo train schedule: the first train leaves at 07:33, while the last ride is at 07:33. A Santeramo in Colle to Milazzo train cost about 45.5 €. But how long is the train ride from Santeramo in Colle to Milazzo? Your journey takes about 13 hours on average.