Sassuolo to Caltanissetta trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Rubiera and arrive at Caltanissetta Centrale every about 4 hours on average. If travelling with Trenitalia, you need to know the Sassuolo to Caltanissetta train schedule: the first train leaves at 17:52, while the last ride is at 18:33. A Sassuolo to Caltanissetta train cost about 144.8 €. But how long is the train ride from Sassuolo to Caltanissetta? Your journey takes about 12 hours on average.