Sassuolo to Niscemi trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Rubiera and arrive at Niscemi every about 12 hours on average. If travelling with Trenitalia, you need to know the Sassuolo to Niscemi train schedule: the first train leaves at 17:23, while the last ride is at 17:23. A Sassuolo to Niscemi train cost about 265.45 €. But how long is the train ride from Sassuolo to Niscemi? Your journey takes about 23 hours on average.