Sassuolo to Palermo trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Rubiera and arrive at Palermo Notarbartolo every about 2 hours on average. If travelling with Trenitalia, you need to know the Sassuolo to Palermo train schedule: the first train leaves at 09:23, while the last ride is at 21:26. A Sassuolo to Palermo train cost about 106.3 €. But how long is the train ride from Sassuolo to Palermo? Your journey takes about 16 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Sassuolo to Palermo and find low cost tickets starting from 63 €!