Sassuolo to Syracuse trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Modena, Salerno and arrive at Siracusa every 60 minutes on average. If travelling with Trenitalia, you need to know the Sassuolo to Syracuse train schedule: the first train leaves at 00:01, while the last ride is at 22:32. A Sassuolo to Syracuse train cost about 87.9 €. But how long is the train ride from Sassuolo to Syracuse? Your journey takes about 16 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Sassuolo to Syracuse and find low cost tickets starting from 41 €!