Sassuolo to Syracuse trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Modena, Salerno and arrive at Siracusa every 60 minutes on average. If travelling with Trenitalia, you need to know the Sassuolo to Syracuse train schedule: the first train leaves at 00:01, while the last ride is at 22:32. Thanks to Trenitalia, offers, you can save on your trip from Sassuolo to Syracuse and find low cost tickets starting from 41 €! If you need to travel this week, prices range from 27.75 € to 27.75€. Booking your train ticket a few weeks in advance though, you can find low cost trains from Sassuolo to Syracuse with fares starting from 12.90€, saving 53% on average.